Title: ETH_Sem3 / OC-I-Reactions (Wennemers)

Carbamic acid

General Nucleophilic addition reaction

General addition-elimination reaction

General reaction at alpha carbon

General acid-catalyzed hydrate formation

General acid-catalyzed hemiacetal formation

General acid-catalyzed acetal formation

Addition of water to an acetal

addition of water to a cyclic acetal

Base-catalyzed hydrate formation

Acid-catalyzed formation of imines

acid-catalyzed formation of hemiaminals

Strecker synthesis

Formation of cyanohydrins

acid-catalyzed enamine formation

acid-catalyzed oxime formation

Q: acid-catalyzed formation of hydrazones
A: SUSBTITUENT SHOULD LOOK LIKE IN UPPER PICTURE
Reaction mechanism analogous to oxime formation:

Mechanism for the reaction of organometallics (Mg) with aldehydes and ketones

Mechanism for the reaction of organometallics (Mg) with carbonyl compounds

Formation of Esters from carboxylic acids via Fischer esterification

Acid catalysed ester hydrolysis

Base catalysed ester hydrolysis

Ester formation from acid chloride

Ester formation from acetic anhydride

acid catalysed transesterification mechanism

base catalysed transesterification mechanism

Preparation of acid chlorides using thionyl chloride

Reaction of acid chlorides with alcohols

Reaction of acid chlorides with amines

preparation of acid chlorides using thionyl chloride

DMF catalysis of acid chloride synthesis using thionyl chloride

preparation of acid chlorides using oxalyl chloride

Preparation of acid chloride in case of acid labile compounds

Formation of amides from acid chlorides

Formation of amides from esters

amide hydrolysis

acid catalysed amide hydrolysis

base catalysed amide hydrolysis

Ester Formation from acids using caesium carbonate and methyl iodide

DMAP as catalyst in nucleophilic attack onto acid chlorides

DCC as coupling reagent in amide formation from acid

Reaction of esters with organometallic reagents

Mechanism of nitrile hydrolysis under basic conditions

Amide formation from acids and amines

Amide formation from acid chlorides with amines

Amide formation from esters and ammonia

Meerwein-Pondorf-Verley reduction

Luche reduction

Reduction of esters to alcohols

Selective reduction of esters and amides to aldehydes via DIBAL

Reduction of esters and carboxylic acids to aldehydes via Weinreb amides

Reduction of imines to amines

Hydroboration of alkenes and oxidative workup (Mechanism)

amide or acid reduction using borane

Clemmensen reduction

Wolff-Kishner reduction

oxidation of aldehydes with permanganate

Oxidation of  secondary alcohols with chromium

Oxidation of alcohols to aldehydes or ketones using TPAP

Oxidation of alcohols to aldehydes or ketones using TEMPO

Swern oxidation

Moffat Oxidation

Corey-Kim Oxidation

Synthesis of DMP

Oxidation of alcohols using DMP or IBX

Pinnick oxidation

amide formation from alcohols an isocyanates

reduction of carbonic acids to alcohols

shapiro reaction

Formation of aldehydes or ketones from Weinreb amides

Synthesis of weinreb amides from acid chlorides

Bouveault-Aldehyd-synthesis (ex. with DMF)

Synthesis of Isocyanates

Deprotection reaction of the Boc-Protection group

Acid catalyzed enol formation

Base catalysed enol formation

acid catalysed alpha halogenation of enols

Base catalysed alpha halogenation of enols

Haloform Reaction

Formation of Silylenolethers

Prevention of double alkylation via enamines

selfcondensation of acetaldehyde

self condensation of acetone

claisen-schmidt condensation

Mukaiyama-Aldol-reaction

Mukaiyama

Henry reaction

Mannich reaction with preceding formation of the Eschenmoser-salt

Formation of the Eschenmoser-salt

Mannich reaction

Pictet-Spengler reaction

Michael addition

Knövenagel-reaction

Base catalysed aldol addition

acid catalysed aldol addition

Base catalysed aldol condensation

Acid catalysed aldol condensation

Mannich

Claisen condensation

Reaction of ketone enolates with esters

retro claisen condensation

Robinson annulation

Enamine anlogous of the Robinson annulation

Dieckmann condensation

Perkin condensation

Darzens reaction

Reformatsky reaction

thorpe-ziegler reaction

(using NaOEt)

Paal-Knorr Furan synthesis

Paal-Knorr Pyrrol synthesis

Paal-Knorr Thiophen synthesis

Protection of aldehydes and ketones with acetals

Deprotection of protected aldehydes and ketones when using acetals

Protection of alcohols using silyl ethers

Deprotection of alcohols when using silyl ethers

Protection of carboxylic acids using t-Butyl ester

Deprotection of carboxylic acids when using t-Butyl ester

Protection of amines using Cbz

Deprotection of amines when using Cbz

Protection of amines using Boc

Deprotection of amines when using Boc

Protection of amines using Fmoc

Deprotection of amines when using Fmoc

Corey-Gilman-Ganem oxidation

Corey-Kim oxidation

Dess-Martin oxidation

Pfitzner-Moffatt oxidation